Indocin is used to relieve moderate to severe pain, tenderness, swelling, and stiffness caused by osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
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Indocin is generically known as indomethacin. It is an NSAID- Nonsteroidal anti-inflammatory drug. It may be responsible for an enhanced risk of severe and fatal heart & blood vessel disorders for example stroke or heart attack.


Indocin is used for the treatment of moderate-severe rheumatoid arthritis, ankylosing spondylitis and osteoarthritis. It is used for the treatment of gout, some types of bursitis or tendonitis, or mild-moderate pain.

Indocin may block some substances in the body which cause inflammation. NSAIDs are used to treat inflammation and pain. They cannot be used for the treatment of the disease because of which these symptoms have occurred.

How to use

Utilize Indocin as coordinated by your specialist. Check the mark on the pharmaceutical for correct dosing guidelines.

Indocin accompanies an additional patient information page known as Medication Guide. Read it deliberately. Read it carefully every time you get Indocin refilled.

Bring Indocin by mouth with meal. Bring Indocin with a glass of water as coordinated by your specialist.

Side effects

Check with your physician if any of the following most common indocin side effects persist:

  • Constipation;
  • drowsiness;
  • gas;
  • heartburn;
  • diarrhea;
  • headache;
  • stomach pain
  • upset stomach;
  • nausea;
  • vomiting
  • bloody or black/ tarry stools;
  • blood in the urine;
  • variation in the produced volume of urine
  • chest pain;
  • depression;
  • confusion;
  • fast or irregular heartbeat;
  • fainting;
  • fever,
  • persistent sore throat;
  • chills, or
  • numbness of arm/leg;
  • mental or mood swings;
  • one-sided weakness;
  • ringing in the ears;
  • severe headache or
  • rectal bleeding;
  • seizures;
  • dizziness;
  • red, blistered, swollen, or peeling skin;
  • severe/persistent stomach ache or
  • liver problems


Inform your doctor or physician if you suffer from any medical conditions which interact with indocin, particularly if any of the below mentioned conditions apply to you:

  • if you are consuming any prescription/nonprescription drug, dietary supplement or herbal preparation, or
  • history of kidney disorder,
  • diabetes, or
  • liver disease or
  • stomach problems or
  • Parkinson disease,
  • bowel problems (eg, bleeding, ulcers, perforation, inflammation)
  • history of fluid buildup,
  • depression,
  • if you have hypersensitive reactions to food/medicines
  • mood or mental problems,
  • seizures,
  • asthma,
  • mouth inflammation
  • nasal polyps, or
  • if you have hypertension
  • a blood disorder,
  • bleeding or clotting issues,
  • dehydration or
  • if you have bad health,
  • low fluid volume,
  • high levels of blood potassium
  • Low levels of blood sodium in blood
  • you drink alcohol;
  • If you are used to alcohol abuse

Pregnancy and Indocin

Indocin may be responsible to cause damage to the fetus. Avoid the use of this medicine if you are pregnant for above 29 weeks.

Indocin is present in maternal milk. Avoid breast-feeding your baby during the intake of Indocin.

Indocin belongs to a group of medicines known as NSAIDs. Indomethacin is the generic name of Indocin and comes in brands Indocin and Indocin SR. The drug is prescribed for inflammation and pain caused by several conditions such as gout, arthritis, bursitis, tendonitis and ankylosing spondylitis.

Indomethacin is likely to develop stomachache if not taken with food or milk. As the drug has to be released slowly into the body, it should not be broken, crushed or chewed. Indocin should have to be swallowed whole, which helps in the slow absorption of the drug into the body.

Indomethacin may augment the risk of heart related issues or circulation problems. If the drug is used for a longer period, then the risk is higher. A person is not advised Indocin just before or after a heart surgery. The drug is also known to increase the risk of perforation or bleeding, which could be fatal. This risk is mainly seen in older people. In case of any stomach pain or bloody tools, or cough mixed with blood or any other uneasiness, a person should not delay in consulting the doctor. A delay will cost a person severely.

Alcohol should be completely avoided while using indomethacin. This is because alcohol increases the risk of bleeding in stomach. It is also advised not to buy any cold, pain or allergy medicines from the drug stores without the doctor’s prescription. In any case you are bound to take such medicines, better see that the medicines that you buy do not contain ibuprofen, aspirin, naproxen and ketoprofen.

There are certain medical conditions that the doctor will analyze before prescribing indomethacin. The doctor may either change the level of dosage or recommend some other drug if a person has a history of clots, stroke or heart attack, high blood pressure, bleeding, stomach ulcers, seizure, kidney problems, liver issues, polyps and asthma.

The doctors will not be instructing indomethacin during the period of pregnancy. Indocin drugs can lead to many complications in an unborn child. Moreover, the medicine is also not prescribed for women who nurse their newborns. It should also be noted that drug Indocin is not prescribed for children who are below 14 years of age. If at all given, the children should be under the constant watch of the doctor.

Now talking of the side effects, a person using indomethacin can come along severe and mild side effects. Some of the harsh side effects include chest pain, slurred speech, vision problems, weakness, balance problems, breath shortness, black or bloody stools, swelling, rapid weight gain, less urinating, cough with blood stains, stomach ache, nausea, dark urine, yellowing of skin and eye sore throat, nausea, peeling of the skin, rashes, muscle weakness, numbness, bruising and tingling. The mild side effects seen in some persons include mild heartburn, constipation, diarrhea, stomach upset, bloating, dizziness, gas, headache, itching, ringing in ears and blurred vision. A person feeling any uneasiness should stop taking Indocin and call the doctor at once.