Aciphex is a proton pump inhibitor. The active ingredient is rabeprazole which is dispensed as oral delayed-release tablets (20mg).
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AcipHex is generically known as rabeprazole. It is a proton pump inhibitor which reduces the measure of acid created in the stomach.


AcipHex is used for the short-term treatment of the gastroesophageal reflux disease symptoms (GERD) in adults & children who are of minimum 1 years of age.

AcipHex is utilized only in adults for the treatment of conditions which involve excessive production of stomach acid, like Zollinger-Ellison syndrome.

Aciphex is also used in adults to enhance the healing of ulcers in duodenum or erosive esophagitis.

How to Use

Also, it may be administered with an antibiotic for the prevention of duodenal ulcer due to Helicobacter pylori (H. pylori) infection. AcipHex is generally consumed once in a day. Follow all instructions on the prescription label.

This medicine shouldn’t be given to a kid without proper medical consultation. Some specific forms & strengths of aciphex shouldn’t be administered to a child below the age of 12 years.

Don’t give acipHex Sprinkle to a child below 1 year old.

Use acipHex for short-term only, generally 4 to 8 weeks. You may be recommended a 2nd course of therapy by your doctor if you require extra healing time

During the treatment of H. pylori infection, rabeprazole may be required for just 7 days. The doctor’s dosage information must be strictly followed.

Consume this drug with a glass of water.

Side Effects

Seek emergency medical attention if you observe hypersensitive signs to AcipHex: hives; trouble breathing; swollen face, throat, lips or tongue.

Inform your doctor right away if you have:

  • Watery/bloody diarrhea;
  • Severe stomach pain,
  • Seizure (convulsions);
  • Signs of low levels of magnesium – tremors, dizziness, fast/uneven heart rate; confusion; jerking muscle movements.
  • Kidney problems – urination less/more than usual, rapid weight gain; swelling, blood in your urine,
  • Symptoms of Bleeding

Common side effects of AcipHex may be as follows:

  • Headache;
  • Vomiting
  • Sore throat;
  • Diarrhea,
  • Nausea,
  • Gas,
  • Constipation; or
  • Stomach pain.


Often people confuse heartburn with the initial signs of a heart attack. Avail emergency medical help if you observe chest pain, pain extending to the arm/shoulder, sweating, nausea, sweating, heavy feeling and a common ill feeling.

Avoid the use of aciphex if you show hypersensitive reaction to rabeprazole or:

Tell your doctor if you have any of these to ensure that the use of aciphex is safe for you:

  • Liver disease;
  • Low magnesium levels in blood
  • Osteoporosis;
  • Osteopenia – Low level of bone mineral density.

Pregnancy and Aciphex

This prescription is not anticipated that would hurt an unborn infant. Tell your specialist in the event that you are pregnant or plan to wind up noticeably pregnant.

It is not known whether rabeprazole goes into breast milk or on the off chance that it could hurt a nursing infant. Tell your specialist on the off chance that you are breast feeding an infant.

Drug Uses

Aciphex is prescribed to treat acid reflux related conditions that include heartburn, GERD (gastroesophageal reflux disease), Zollinger-Ellison syndrome, heartburn, stomach ulcers and erosive esophagitis.

Acid reflux occurs when gastric acid travels from the stomach back up the esophagus. Symptoms of acid reflux are chest pain, difficulty in swallowing, heartburn, regurgitation, dental erosion, or hoarseness. Factors that can cause acid reflux include smoking, foods that are high in fat content, caffeine, alcohol, chocolate, and obesity.

The active ingredient in Aciphex reduces the amount of acid produced by the stomach. Aciphex can also be prescribed with an antibiotic to prevent ulcers caused by the H.pylori bacteria.

Aciphex is used to treat other medical conditions not listed in this information guide.


Aciphex must always be used as directed. Do not make adjustments to the dose before speaking to a doctor. Aciphex can be taken with, or without, food. Drink a glass of water with each dose.

The delayed-release tablets must never be chewed, broken or crushed. The tablet must be swallowed whole to ensure that the delayed-release mechanism works correctly.

Continue your treatment with Aciphex as prescribed. Do not stop taking this medication even if there is an improvement in your condition. If, after using Aciphex for eight weeks, there is no improvement in your condition, contact your doctor.

Missed Dose

If you miss a dose, it may be taken when you remember. However, do not take the missed dose near the time of the next scheduled dose. In this case, ignore the missed dose. Never double-up on a dose.

Warnings and Precautions

Do not use Aciphex if you are allergic to rabeprazole.

Before using Aciphex, you must give your doctor full details of your medical history and other medications that you use. These include herbal medicines and vitamin supplements. Aciphex can react badly with some medications.

Aciphex is not likely to harm an unborn fetus so pregnant women are able to use this medication. It is not known if Aciphex is passed into breast milk so women who are breast-feeding should use this drug with caution, under directions of a doctor.

While using Aciphex, your doctor may wish to restrict certain foods or drink in your diet.

Possible Side-effects

Call for emergency assistance if any of the following symptoms of allergy occur: difficulty in breathing, hives, or swelling of the lips, tongue, throat or face.

Less serious side-effects can include upset stomach, diarrhea, nervousness, insomnia, or mild skin rash and itching. These side-effects generally occur in the initial stages of treatment and do not last long.

Contact your doctor if any uncomfortable symptoms occur, or persist.


Overdose with Aciphex is unlikely. However, excessive doses can cause serious symptoms. If overdose is suspected, call for emergency help immediately.

Storage instructions

Aciphex must be kept away from children and stored in a dry, cool place away from sunlight and moisture.